miRò: a miRNA knowledge base

نویسندگان

  • Alessandro Laganà
  • Stefano Forte
  • A. Giudice
  • M. R. Arena
  • Piera Laura Puglisi
  • Rosalba Giugno
  • Alfredo Pulvirenti
  • Dennis Shasha
  • Alfredo Ferro
چکیده

miRò is a web-based knowledge base that provides users with miRNA-phenotype associations in humans. It integrates data from various online sources, such as databases of miRNAs, ontologies, diseases and targets, into a unified database equipped with an intuitive and flexible query interface and data mining facilities. The main goal of miRò is the establishment of a knowledge base which allows non-trivial analysis through sophisticated mining techniques and the introduction of a new layer of associations between genes and phenotypes inferred based on miRNAs annotations. Furthermore, a specificity function applied to validated data highlights the most significant associations. The miRò web site is available at: http://ferrolab.dmi.unict.it/miro.Database URL:http://ferrolab.dmi.unict.it/miro.

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عنوان ژورنال:

دوره 2009  شماره 

صفحات  -

تاریخ انتشار 2009